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The reduced infiltration of inflammatory cells into perivascular and connective tissues was also demonstrated in another study with apigenin treatment (5 mg/kg, 10 mg/kg) (Fig

[DOI] [PubMed] [Google Scholar] 192.Morris B.J., Cochran S.M., Pratt J.A

Although many enzymes in one-carbon metabolism are affected by the sex hormones testosterone and estradiol, the main reasons for sexual dimorphism in glutathione metabolism are the effects of estradiol and the GSH regulatory motif, which includes the inhibition of GS and GCL by GSH itself [Figure 2B]

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REGULATION OF Glutathione SYNTHESIS. Molecular aspects of medicine 30.1-2 (2009): 4259