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Biological activity of selenium: Revisited

J Am Nutr Assoc

As we get older, our bodies produce less elastin, which is why skin can start to sag or take longer to snap back into place

The little blue rectangles are the proteins of interest, fused to GST (purple)

M., Rather, G

4.3 Consequences of mtDNA damage: from bioenergetic crisis to immune exhaustion mtDNA mutations and depletion impair the synthesis of essential ETC components, resulting in defective OXPHOS, reduced ATP synthesis, collapse of the mitochondrial membrane potential (m), and accumulation of metabolic intermediates due to TCA cycle disruption and compensatory glycolysis