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Vaduganathan M, Filippatos G, Claggett BL, Desai AS, Jhund PS, Henderson A, Brinker M, Kolkhof P, Schloemer P, Lay-Flurrie J, et al

doi: 10.3389/fphar.2020.01021 162 JiangTGhoshRCharcossetC

Cells were incubated at 37 C with 5% CO 2 in a humidified atmosphere

Clients with known allergies to B vitamins or any of the MIC compounds should disclose this during intake

Overhead sprinklers sprang to life

To ask how -KG insufficiency depletes the cytosolic NADPH pool, we first confirmed that cytosolic NADPH-producing enzymes ME1 and IDH1 are essential for cell survival during energy stress, as previously reported 26,31 , because knockdown of either gene sensitized Huh7 and H1299 cells to glucose starvation (Supplementary Fig