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Standard doses of 30-100 mcg work well with either morning or evening timing, while higher therapeutic doses may benefit from different approaches

Alcohol Food additives Eating Neurological problems Drugs Other causes of flushing Flushing related to alcohol There is increased susceptibility to alcohol-related flushing in Asians, who have a defective enzyme (acetaldehyde dehydrogenase) leading to a build-up of acetaldehyde

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However, considering the severity and duration of reported symptoms, dehydration was less likely to be the underlying cause

Nature 486 , 554558 (2012)