Last reviewed: May 29, 2026 Last updated: May 29, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
This article covers the biological mechanisms at play, the timing and dosage considerations that matter, and the honest limitations of the current evidence base
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Cell 186:693714 Wu LJ, Zhuo M (2009) Targeting the NMDA receptor subunit NR2B for the treatment of neuropathic pain