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Gastrointestinal Histology As in previous studies [12,13,14,15,16,20,22,23,24], we used a histologic scoring scale adapted from Chui and coworkers [52] for the intestinal tissue damage, scoring 05 (normal to severe) in three categories (mucosal injury, inflammation, and hyperemia/hemorrhage) for a total score of 0 to 15, as described by Lane and coworkers [53]

Thus, the use of this approach allowed to identify an original target, the protein kinase DYRK1B, suggesting that an inhibitor of this protein could present a possible senolytic activity 40

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Storage Requirements by Form Stability Indicators The characteristic blue tint of reconstituted GHK-CU comes from the copper ion

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An animal study demonstrated the potential causative role of the gut microbiota in the development of NAFLD (Reference Aron-Wisnewsky, Vigliotti and Witjes6)