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La aparicin espontnea de mltiples mculas hiperpigmentadas sobre la mucosa bucal y labios sin la presencia de enfermedad sistmica subyacente fue reportada en 1970 por Laugier y Hunziker, llamndole inicialmente pigmentacin melnica lenticular esencial de la mucosa bucal y labios3
Merck KGaA) and MK-2206 (500 nM, MedChemExpress, New Jersey, USA), respectively
VRK2 activates TNF/NF-B signaling by phosphorylating IKK in pancreatic cancer
