McCarty concluded
Low-fat meals in general are your friend during the titration phase
While some patients report vasomotor symptoms during treatment, there is no established pharmacological mechanism directly linking tirzepatide to hot flashes
Any claims about its benefits outside of such controlled settings should be treated with significant caution
doi: 10.3389/fmed.2026.1752341 Received 23 November 2025 Revised 04 April 2026 Accepted 10 April 2026 Published 29 April 2026 Volume 13 - 2026 Edited by Wei Liu, Huazhong University of Science and Technology, China Reviewed by Jheng-Yan Wu, Chi Mei Medical Center, Taiwan Jennifer Teske, University of Arizona, United States Updates Copyright 2026 Fang, Zhu, Rao and Liu
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