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Success with either medication requires commitment to healthy lifestyle changes, regular medical monitoring, and patience with the process

For obesity medicines specifically, NICE has historically applied criteria around BMI thresholds (in kg/m), comorbidities, and specialist service settings

Metformin helps manage blood sugar, increases insulin sensitivity, suppresses appetite, reduces visceral fat, and benefits gut healthall factors that may help with weight loss

Key details Treatments include compounded semaglutide in injection and oral tablet formats and compounded tirzepatide as an injection

This combination can reinforce unhealthy relationships with food and eating restriction in vulnerable individuals

Moving the drops around