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"Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 trial." Lancet , 398(10313), 1811-1824

The exact mechanism how it works is not fully understood

An et al., 2022)

GLP1 GLP-1-1 GLP1GLP-12 GLP1 GLP-1 GLP-1 BMIkg (m) 2 25 GLP-1 GLP-1 GLP-1GLP-1 15 61012 12 120mL303mg1117mg 1,6501,100 QA 3mg7mg 3mg3mg47mg14mg 2 GLP-1 30 3030 2 GLP-1 2 GLP-1FDA28

Adiponectin has also been observed to inhibit TNF- production, which might be an important target for treating obesity-related asthma [29]

based popular nutrition supplement brand GNC conducted a first-of-its-kind nutritional analysis of GLP-1 users, revealing widespread deficiencies in essential nutrients and protein intake