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MMP, a key indicator of mitochondrial functionality, was assessed using JC-1 dye, which differentiates between energized and depolarized mitochondria

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148 The ADA2 activation domain binds to the histone methyltransferases CARM1 (co-activator-associated arginine methyltransferase 1) and PRMT1 (protein arginine N-methyltransferase 1) to facilitate transcription activation