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Originally developed by Novo Nordisk in the mid-1990s, it was characterized in pivotal research by Raun et al

Glutamate Cysteine Ligase (GCL) : This enzyme helps begin the first step in making glutathione

Zivot A, Lipton JM, Narla A, Blanc L

These elements are intricately associated with the activation of ROS generation, which is mediated by protein kinase C (PKC) and subsequently results in the activation of the downstream transcription factor, NF-B (Ming et al., 2022)

doi:10.1111/j.1471-4159.2006.03693.x PMID: 16539679 4

That way, after you apply, you can also remove dead skin cells as you swipe the pad across your face leaving the product behind to continue to work