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Integrative aging characteristics emerge when the cumulative impairment caused by primary and antagonistic aging characteristics fail to be repaired, resulting in stem cell exhaustion, chronic inflammation, dysbiosis and altered intercellular communication, 39 all of which collectively determine the speed of aging (Fig

The risk is particularly high in those with abdominal obesity (Pak 2016

One possible candidate for such a link is oxidative stress

Osmolality measurements The osmolality of all the urine samples was measured at Ampath Laboratories, South Africa, by determining the freezing-point of each sample using an Advanced Osmometer (model 3320)

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