The most common retatrutide side effects are nausea (28%), diarrhea (24%), constipation (21%), and vomiting (17%), with symptoms peaking around weeks 6-8 before substantially improving by week 12
Journal of the International Society of Sports Nutrition
Specifically in regard to nausea, it tended to be most pronounced in the first 4 weeks of therapy in all phase III LEAD trials, with symptoms generally dissipating over the remainder of the study period
We've known for decades that it's a combination of biology, genetics, physiology, environment, social drivers of health
GLP-1 molecules are big peptides that the body breaks down very fast
Ozempic, Wegovy, Mounjaro, and Zepbound all belong to a class of drugs called glucagon-like peptide-1 receptor agonists, or GLP-1 receptor agonists