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Doses are usually low and delivered in short pulses or continuous infusion based on effect needed, which makes stimulation targeted and controllable compared to more general agents

Human data is limited and it is not FDA-approved for any indication

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Lassegue B, Griendling KK

Impairments in the ETC can lead to electron leakage and the excessive generation of reactive oxygen species (ROS)

Several studies suggest that adequate levels of 25(OH)D are associated with better glucose control, particularly in individuals with insulin resistance or T2DM ( In terms of lipid modification, we found no association between 25(OH)D categorization and lipid reduction