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Additionally, de Boer et al
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MGF and Large Animal Cardiac Research In sheep treated with the MGF E-domain peptide following microsphere-induced myocardial infarction, cardiac function improved in MGF E-domain-treated animals versus vehicle controls, with 35% less compromised cardiac muscle, absent immunostaining for cleaved caspase-3, and preservation of both systolic and diastolic function leading the authors to conclude that the E domain of MGF protects the myocardium against ischaemia and improves cardiac function post-MI
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Feng et al., 2002)
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