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Understanding whether B12 injections require refrigeration depends on the specific formulation

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Based on the data available in 2015, EFSA did not identify any known health risks associated with the use of dietary supplements, so no maximum dose or maximum daily intake, also known as a tolerable upper intake, was set (EFSA, 2015)

These characteristics, combined with its demonstrated bioactivity across diverse tissue types, suggest it may serve as a model compound for further pharmacological exploration

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