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It is a **chronic metabolic disease** associated with: Type 2 Diabetes Hypertension Dyslipidemia Cardiovascular disease Fatty liver disease (MASH) Sleep apnea Despite effective therapies, many patients hesitate to start treatment because injectable medications can affect adherence

Its the same drug, just a different dose

The committee defined the objectives, the key issues and identified the guidelines key questions and developed them following the PICO format: P patient, problem, or population, I intervention, C comparison, control or comparator, O outcome

Back Thorens, B, Porret, A, Bhler, L, et al (Nov 1993) Cloning and functional expression of the human islet GLP-1 receptor

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The safety of GLP-1 receptor agonists during breastfeeding has not been well-studied