After subcutaneous injection, it reaches peak plasma concentration (Tmax) in 1 to 3 days
Another SHE Media member, Gina Vaynshteyn (AVP, Commerce), also started a GLP-1 program postpartum
The first goal of these trials was to prove GLP-1 receptor agonists cardiovascular safety, and majority of CVOTs were designed as non-inferiority trials
As the authors note, GLP-1 receptors are expressed in many regions of the brain and in particular in the arcuate nucleus and other hypothalamic regions involved in the regulation of food intake
One obvious advantage of the small molecule agonists in the replacement of peptide GLP-1 analogues is that they could be administered orally, thus avoiding the discomfort of subcutaneous injections and increasing the compliance of patients
BGM is needed before meals to give the user the chance to adjust the meal insulin dose if the pre-meal glucose is out of range at the time, while measurements over a few days will show whether the doses active before that meal require adjustment
