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At the at least 20% weight-loss threshold, CagriSema ranked first at RR 27.82, followed by tirzepatide 15 mg at RR 23.70

Due to their selective enhancement of certain beneficial gut bacteria and their ability to modify the composition and function of the gut microbiota, prebiotics are considered a potential supportive treatment for various disorders such as IBS, Crohns disease, issues with bowel motility, autism, obesity, and colorectal cancer [92]

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Adler, V

Therefore, tissue distribution data should be interpreted within the context of metabolic transformation and circulating species