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5,6 The JAMA review concludes that though the WHI data stands to recommend against the use of HRT in older women for prevention of chronic diseases, treatment of women in early menopause for vasomotor symptoms is appropriate outside of specific contraindications

Hundreds of millions of people worldwide suffer from Type 2 diabetes, which can lead to kidney failure, blindness, and amputation

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It is often used when diet and exercise alone are insufficient to manage blood sugar levels

Consideration of such secondary contributions can obviate the need for unnecessary testing and inappropriate treatment