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Sinclairs Dosage: Not specifically listed in Sinclairs recent published regimens, though he has mentioned it in broader discussions

For example, the variant 677T is most commonly associated with cerebral vascular accident (stroke), elevated homocysteine, cardiovascular disease risk, peripheral neuropathy, deep vein thrombosis, early-onset heart disease, stillbirth, neuro-tube defect, cleft lip, and preeclampsia

10.1016/j.ejphar.2021.174613 62 LiX

Additionally, research on the interactions between the gut microbiota and nutrients is still inadequate, and the specific mechanisms underlying these interactions remain unclear

These gender-specific effects may be important for the side effects of ibuprofen (such as increased risk of stroke) and more research is needed to investigate this possibility

It may also trigger asthma attacks, macular erythema, red spots, or tiredness in some people