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Oxidative stress-induced endothelial dysfunction probably represents one of the first stages in the development of atherosclerotic lesions ( It has been observed in animal models that levels of several anti-oxidant enzymes decline during atherogenesis ( Another study analyzed the effects of HOTYR on anti-oxidant status and the progression of aortic lesions in hyperlipemic rabbits

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Standard titration keeps you on 0.25 mg for 4 weeks before advancing to 0.5 mg