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In addition to its well-known role as a hormone, a plethora of evidence has been put forth in support of its role as a neuroprotectant, immune modulator, and even as an antioxidant for the brain and body

Absorption is also a genuine issue with standard berberine formulations

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Thus, it should be clear that any disruption in the level of NADPH may have a profound effect upon a cells ability to deal with oxidative stress