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Children and adolescents retatrutide has not been studied in paediatric populations and should not be used outside of approved clinical trial settings

4) Can GLP-1 Medications Cause Thyroid Nodules or Swelling

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Since then, the Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity (SELECT) cardiovascular outcomes trial has shown that semaglutide 2.4 mg once weekly was associated with a significant 20% relative risk reduction in major cardiovascular adverse events compared with placebo [38]

TRIUMPH1 also has a nested OA trial that, similar to the TRIUMPH4 standalone OA trial, includes participants with obesity with knee pain and radiographic evidence of knee OA