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Although THC possesses neuroprotective antioxidant properties through non-CB1R pathways [33], it also upregulates plasma inflammatory cytokines [34], increases vulnerability to ischemic stroke in young people [35], increases mitochondrial dysfunction [36, 37] and alters gene pathways associated with mitochondrial oxidative phosphorylation [38]

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Nat Rev Immunol 13(11):790801 Weiss GA, Hennet T (2017) Mechanisms and consequences of intestinal dysbiosis

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