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While dexamethasone only modestly reduced synovial inflammation, it failed to prevent cartilage deterioration, whereas liraglutide significantly enhanced pain thresholds, lowered synovial scores, and preserved cartilage integrity, with 60 g doses notably reducing overall joint damage [140]

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Stress itself typically does not cause melena, but it may exacerbate underlying conditions such as gastritis or ulcers that can lead to bleeding

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