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Bone marrow-derived stem cell (BMSC) transplantation was found to counteract IVD degeneration and/or increase the proteoglycan content of IVDs in experimental rabbit and mouse models [7, 30, 4851]

Los investigadores utilizan con frecuencia el DSIP en modelos experimentales controlados diseados para explorar los mecanismos de comunicacin intracelular, las redes de sealizacin peptdica y los sistemas de regulacin molecular

Dong LG, Lu FF, Zu J, Zhang W, Xu CY, Jin GL, Yang XX, Xiao QH, Cui CC, Xu R, Zhou S, Zhu JN, Shen T, Cui GY (2020) MiR-133b inhibits MPP+-induced apoptosis in Parkinsons disease model by inhibiting the ERK1/2 signaling pathway

It has been shown that MSCs increase tensile strength through a macrophage-dependent mechanism in wound healing in old mice, restoring the strength levels seen in younger adult mice (Lee et al., 2013)

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