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Sedenho-Prado LG, Yugar LBT, Whitaker AR, Martins MP, Jesus DC, Ferreira I, et al

New England Journal of Medicine , 390(8), 712-724

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A novel phytochemical, DIM, inhibits proliferation, migration, invasion and TNF-alpha induced inflammatory cytokine production of synovial fibroblasts from rheumatoid arthritis patients by targeting MAPK and AKT/mTOR signal pathway