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As of 2026, retatrutide is an investigational drug in Phase 3 clinical trials (the TRIUMPH program)

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How long nausea lasts depends on the medication and dose and is most pronounced when beginning the medication or increasing the dose

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Wegovy dosing schedule: Weeks 1-4: Starting dose 0.25 mg once weekly Weeks 5-8: 0.5 mg once weekly Weeks 9-12: 1 mg once weekly Weeks 13-16: 1.7 mg once weekly Weeks 17+: 1.7 or 2.4 mg once weekly The recommended maintenance dose of Wegovy in adults is 1.7 or 2.4 mg once weekly