Exploratory whole-exome DNA sequencing (Supplemental Material) indicated that total carnitine levels in individuals with a CPT2 gene mutation ( n = 8, 44.5 7.9) versus those without ( n = 14, total carnitine = 36.57.7) were significantly higher (t = 2.321, p = 0.031, d = 1.029, CI95% = 1.942 to 0.093), and free carnitine levels were lower in those with the SLC22A5 mutation ( n = 2, 19.0 5.7) versus those without ( n = 20, 31.3 6.9) the mutation (t = 2.420, p = 0.025, d = 1.795, CI95% = 0.220 to 3.330)
StatPearls, NCBI Bookshelf
& Ceriello, A
The high-dose vitamin C therapy has boosted my energy levels
However, although weight loss was observed in some studies, it did not occur in all studies (2)