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Endogenous MOTS-c levels decline with age

Metformin Metformin has been FDA approved and used for the treatment of diabetes and polycystic ovarian syndrome (PCOS) for over 25 years

Polyamines in the gut includes cadaverine, putrescine, and spermidine, although bacteria can produce other polyamines

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In the present study, the beneficial effect of Gln supplementation on inflammation was only mild to moderate, which may be due to the shorter infection period compared to that described by Hagen et al

Include A1C, fasting glucose, BMI, and weight history