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Liu J, Clough SJ, Hutchinson AJ, Adamah-Biassi EB, Popovska-Gorevski M, Dubocovich ML

Most evidence for MIC B12 is anecdotal or from small uncontrolled studies

The standard escalation schedule takes 1620 weeks, starting at 0.25 mg and increasing by 0.25 mg each week for the first four weeks, then increasing by larger increments every four weeks thereafter

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