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For qPCR assays, total RNA samples were extracted from PC-3 cells or LNCaP cells, clinical specimens, or subcutaneous tumors

However, the optimization of treatment route and dosage requires further research

71 Acyl-CoA synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3) were firstly identified as key enzymes which promote PUFAs into PLs for forming PL-PUFAs and induce ferroptosis

Oral dosing ranges discussed in research community use Phase Weeks 12 (start low) Daily dose 50 mg once daily Notes Morning dosing is the pattern most often reported

These findings indicate that BPA exposure during development has persistent effects on ERK, JNK, and AKT pathway activation in the retina, with effects depending on the age of exposure and BPA concentration

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