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Considering that Y1R and Y2R are expressed in other brain regions within corticostriatal-limbic circuitry, more work is needed to determine the mechanism behind the therapeutic effect of these drugs

187 The incretin hormones play a crucial role in maintaining metabolic homeostasis via augmentation of insulin secretion from islet-beta-cells: the incretin effect accounts for 6070% of total insulin released from the pancreas during the postprandial period

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J Pediatr Endocrinol Metab 17:55-66, 2004

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