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Retatrutide has reported a larger average weight-loss effect than tirzepatide (the active ingredient in Mounjaro and Zepbound) in their respective trials roughly 28% versus roughly 2122% over similar timeframes largely because retatrutide adds a glucagon receptor on top of the GIP and GLP-1 targets tirzepatide already uses
Twenty units here is right on target
Joel Bervell on this episode of The Dose podcast to talk about the state of obesity care in the United States
NNMT-related research is relevant to models involving adipocyte biology, NAD+-associated pathways, methylation-linked metabolism, and cellular energy regulation
Limit excess sodium, added sugar, and saturated (bad) fats, which can lead to heart issues, poor blood sugar control, and worsen gastrointestinal side effects of semaglutide, like bloating and abdominal pain