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Description

Nature 539 , 187196 (2016)

Efficacy and safety of rivastigmine in patients with Alzheimer's disease: international randomised controlled trial BMJ 1999

The platform provides several formulations designed to address different patient needs and preferences

A total of 160 (group 1) and 122 (groups 2 and 3) participants would need to be randomised to confirm bioequivalence for all three groups for AUC 024h,SS , assuming that 85% of participants would complete the steady-state periods