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[2] The end-replication problem the biochemical inevitability that DNA polymerase cannot fully replicate the 3' end of linear chromosomes means that 50200 base pairs are lost with each S-phase

Therefore, we estimated a total annual burden of 400,464 hours for all hospitals (7,416 hospitals 54 hours) at a cost of $36,519,350.40 (7,416 hospitals [($128/hour 2 hours) + ($87.52/hour 40 hours) + ($97.30/hour 12 hours)])

These three timelines intersect in ways that determine whether you'll need one vial or several for your research protocol