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Leoung GS, Stanford JF, Giordano MF, Stein A, Torres RA, Giffen CA, et al

Sun and collaborators, with the aim of synthesizing a nonpurine compound that could inhibit the XO enzyme, proposed pyrimidine derivatives, a class of compounds widely used in medicinal chemistry with previously reported inhibitory potency, combined with amino or hydroxy groups as pharmacophores in their development

*The Food and Drug Administration has not evaluated these statements

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