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During gall stone formation, in addition to classical rhomboid-shape monohydrate crystals, cholesterol can also crystallize transiently as needle-, spiral-, and tubule-shaped crystals of anhydrous cholesterol (Dowling 2000)

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The table says dehydration risk is amplified by GLP-1-induced nausea and reduced intake for people on thiazides or loop diuretics, and it lists monitoring electrolytes and fluid status as the clinical consideration, with a diuretic adjustment if needed

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