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6 / A peracetylated β-D-lactose ligand equipped with an azide-functionalized linker through a short ethyl spacer
/ MUC1(126-149)-STn(130) / Mucin1
5 / / Acalabrutinib-d4 / Calquence-d4
32 / A synthetic heparan sulfate (HS) / heparin disaccharide bearing iduronic acid (IdoA) linked to 2-N-sulfated glucosamine (GlcNS)
/ MUC1(135-145-Lys(5-FAM))-STF(139) / Mucin1
PE934030: Galβ(1-3)GalNAc-α-PEG3-Azide label-new 6 / A peracetylated β-D-lactoseC20H36N4O13 540. 52 A core 1 T antigen (Gal1 3GalNAc) ligand equipped with an azide handle through a hydrophilic PEG3 spacer. The terminal azide couples to alkynes via copper catalyzed azide alkyne cycloaddition (CuAAC) or to DBCO and related strained alkynes via copper free click chemistry, forming stable 1,2,3 triazole linkages. This compound presents the core 1 T antigen (Gal1 3GalNAc), a tumor associated carbohydrate antigen and ligand for
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