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The body excretes excess B12 through the kidneys, and no Tolerable Upper Intake Level exists because B12 toxicity from dietary sources is extremely rare

Gastrointestinal side effects during titration Nausea, mild GI discomfort, and altered bowel habits are common, peaking in the first weeks and improving with proper dose pacing

Research Evidence Comparison# Retatrutide Research# The pivotal Phase 2 trial (Jastreboff et al., NEJM 2023) enrolled 338 adults with obesity and demonstrated weight reductions of up to 24.2% at 48 weeks

Make sure to incorporate some physical activity, even if its just stretching during long flights or taking a stroll after meals

Second, protein helps you feel satisfied longer