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In Figure3, we show model computations of the rates of the glucoronidation reaction, the sulfation reaction and the cytochrome P450 reaction in the liver at 0.5 hours after the dose for a range of doses

doi: 10.1016/j.cmet.2011.02.001 58 FlintARabenAAstrupAHolstJJ

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Pharmacological advancements in bile acid transport include ASBT inhibitors, which reduce bile acid reabsorption, and MRP2 activator which enhance bilirubin excretion [54]

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