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Research examines its effects on fibroblast activity, extracellular matrix production, gene expression related to tissue remodeling, and oxidative stress models
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Addressing the underlying condition first, or simultaneously, is the clinical approach at Perfect B
Biochimie 93 , 13921400 (2011)
NRF2 is an important regulator for maintaining intracellular redox homeostasis, upregulating the expression of various genes involved in iron and ROS metabolism (NQO1, HO1, and FTH1) through the p62-Keap1-NRF2 pathway and inhibiting cellular ferroptosis [62]
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