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The cerebral spinal fluid fills the spaces, or ventricles, surrounding the different regions of the brain.[ref][ref] (Ill come back to how this impacts brain health and Alzheimers disease.) As you age , the pineal gland will start to calcify, or build up calcium deposits

It signals fibroblasts to build collagen and elastin, activates angiogenesis (new capillary growth), reduces inflammatory cytokines like TNF-alpha, and helps stem cells migrate to repair sites

It was first isolated from human plasma, where it naturally occurs at concentrations of around 200 ng/mL at age 20, declining to approximately 80 ng/mL by age 60

doi:10.1128/msphere.00474-22 92

Circulation 110 , 31083114 (2004)

Peptide therapy should only be administered under the supervision of a licensed healthcare provider