In line with these findings, by downregulating the oxidative stress, statins decrease hepatic steatosis through increased hepatic antioxidant paraoxonase 1 (PON1) activity (Samy and Hassanian, 2011), and increase mitochondrial and peroxisomal oxidation, as well as expression of an FAO regulator PPAR-alpha (Park et al., 2016)
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Currently approved GLP-1 receptor agonists in the United States include semaglutide (Ozempic, Wegovy, Rybelsus), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and exenatide (Bydureon BCise)
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