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Type 1 contains vildagliptin and saxagliptin, which bind only to the S1 and S2 subsites and form a covalent bond with the nitrile group of their cyanopyrrolidine moiety and Ser630 of DPP-4

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Efficacy in Weight Reduction Retatrutide has demonstrated remarkable efficacy in weight reduction, making it a promising candidate for obesity treatment

PMID 16492800

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