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Considering the pharmacokinetics of human growth hormone (hGH), the common practice of administering subcutaneous human growth hormone (hGH) injections in the evening between 20:00 and 21:00 leads to a peak in hormone levels approximately 46 hours later, aligning closely with the natural nocturnal surge that typically occurs around midnight to 02:00 (23)

Applicable Procedure Codes: G0276, G0293, G0294, G2000, S9988, S9990, S9991, S9992, S9994, S9996

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Kostoglou-Athanassiou, I., Athanassiou, P., Lyraki, A., Raftakis, I., & Antoniadis, C

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Most users report sleep normalizing by the end of week 2 without any changes to their protocol