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Conor Sheehy - PharmD, BCPS Edited By: Kari Asadorian - BSN, RN Last updated: B12 Injections vs
44 An open-label, uncontrolled trial in 51 patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) found improvements in 34 patients after 3 months of supplementation with hydroxo-B12, 10 000 mcg twice per week as nasal drops
Purity is absolutely paramount for both compounds, as contaminants can skew research results and introduce confounding variables
Specificity is not the same as safety
This might sound high compared to the NIH's Recommended Dietary Allowance of just 2.4 mcg daily for adults, but don't worry the injection method allows for safe delivery of these higher doses, and B12 is water-soluble, meaning your body efficiently eliminates any excess
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