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Insmeds Iplex however was an IGF-1/IGFBP-3 complex called mecasermin rinfabate (iPlex TM ) [90] designed to better mimic IGF-1s natural state and thus reduce side effects whilst also increasing its circulatory half-life [91,92]
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doi: 10.1016/j.pharmthera.2006.07.001 74 HostetlerG
Because of drug shortages and accessibility issues, FDA-approved compounding pharmacies are permitted to create bioidentical versions of these medications
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